de Pablo Group: Emre Sevgen

Graduate Student

de Pablo Group

Research

Crystallization-driven self-assembly can drive formation of supramolecular assemblies into fibrils and spherical micelles with applications in immunology and drug delivery. A better understanding of the interplay between polymer physics and chemistry and their influence on important parameters such as drug release profile, particle size, stability and transport/clearing can guide development of better nanoparticles. My project includes all-atom molecular dynamics to elucidate self-assembly mechanisms and kinetics, development of nanocarriers for cancer immunotherapeutics based on those results, and investigation of basic polymer physics of fibrillar micelles using both experimental methods such as extensional flow in microfluidics as well as computational results.

Biography

Emre is from Istanbul, Turkey. He got his bachelor's degree from the University of Illinois at Urbana-Champaign in 2013, where he studied chemical engineering, bioengineering and mathematics. He is currently pursuing a Ph.D in molecular engineering at the University of Chicago, co-advised by Prof. Juan de Pablo and Prof. Jeffrey Hubbell.

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